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As you are probably well aware we are passionate about dermal rolling and why not an inexpensive, non-invasive, highly effective little tool that has a multitude of benefits for your skin. Naomi did a lot of research and trials before settling on the green .05 mm rollers that we sell but in a never ending quest for optimum results we have come
across some important research that has changed the rolling protocols we had previously Based on the research of Dr Lance Setterfield M.D. who has been researching skin rolling
for over 5 years we are advising that you only roll with the .05 roller once a month,
that’s right once a month!
The reason being is that this length of needle is the length that causes a micro trauma by creating minute punctures in the skin at the basal layer resulting in a mild inflammation response that initiates collagen induction. Rolling with this length of needle will also stimulate the skin’s wound healing mechanism consisting of anti – fibrotic, pro –fibrotic, Rolling more than once a month with the 0.5 will cause collagenase to be permanently peaked and this will break collagen down as fast as you make it. Collagenase is a protein that attacks the protein bonds of collagen hence destroying it. Treating once a month allows the healing cascade to follow the normal pathway. Also too frequent rolling with a 0.5 results in too much of a inflammatory response, and we want to minimize this. But remember there is more to rolling than just collagen production, there is a great
textural improvement in the skin, increased product absorption and increased
circulation. These benefits can be obtained by using a 0.3 mm roller (cosmetic roller)
4 times per week without creating any trauma to the skin. In summation our new rolling
• Roll or have a Salon treatment once a month with a 0.5mm roller to stimulate collagen production, treat deep lines and scarring. • Use a 0.3 mm 4 times per week to increase micro circulation, improve product Sound To Good To Be True? Well It Is True, this is a proven
method that will greatly benefit your complexion giving you a
Healthier, Rosier, Plumper And More Youthful Look.
How Does It Work?

Similar techniques have been used in traditional medical systems safely for thousands of
years. These treatments are designed to mimic cosmetic acupuncture treatment without
having to administer acupuncture. Like Cosmetic Acupuncture, Skin Rolling (Collagen
Induction Therapy CIT) is a harmonious pairing of health and beauty.
CIT is a very safe, natural and holistic approach to beauty.

The trans dermal roller is gently rolled in specific directions over the skin on the face from
3 – 5 minutes. The trans dermal roller contains 192 surgical stainless steel micro
needles that come in a range of needle lengths with a 0.3 mm gauge, (thickness). The
tiny needles cause a micro trauma by creating minute punctures in the skin resulting in a
mild inflammation response that initiates collagen induction. No! it’s not painful!

The reason why there is this collagen stimulation is that there is not a full blown wound
response in the tissue i.e. the dermal roller does not injure any tissue so little collagenase
is stimulated (collagenase is a protein that attacks the protein bonds of collagen hence
destroying it). The increased stimulation of the facial skin cells also releases TGF-
(Transforming Growth Factors) into the dermis. TGF beta is a protein that controls cell
proliferation and cellular differentiation among other functions in most cells. This cell
multiplication results in the formation of new tissue layers of elastin and collagen fibres
(neo-collagenosis) as well as the formation of new capillaries for a improved blood supply.
The result is that both epidermis and dermis vitality will improve and become thicker.
The length of the needles on the roller is of upmost importance, collagen stimulation hence
production can only be achieved by using a 0.5mm and above needle length as it is a
scientific fact that new collagen regenerates close to the corneum (the outermost layer of
the skin), no deeper than 0.5 to 0.6 mm below the basal layer (The deepest layer of the
epidermis). Rolling the skin with needles less than .5mm in length will enhance the flow
active substances through the stratum corneum and circulation but will not induce the
production of collagen and elastin.

It has been scientifically proven that the dermal roller increases collagen induction C.I.T increases absorption by up to 10,000 times. It achieves this as the dermal roller when rolled across the skin causes micro channels at the skins surface. This enables the skin to absorb a product applied to the top layer, hence it enters the blood stream directly.

Frequently Asked Questions.

What skin conditions can benefit from CIT?
All skin types will get a marked textural improvement but aging and post acne scarred skin
will show the most dramatic improvement.
The dermal roller can be used to treat the following conditions
Sagging Skin - Hyperpigmentation - Cellulite - Stretch Marks - Scarring,
Hair Loss - Ageing skin - Wrinkles - Thin Skin - Enlarged Pores - Blackheads
Acne/Rosacea - Spider Veins - dilated blood vessels - Dull Complexion -
Uneven Skin Tones.

How soon will I see an improvement in my skin?
Most people see an improvement in their skin texture in around 7 days. To build a good
basic level of collagen it is best to use your roller once a month in the evenings.
For those 35 years and under, use for 3 months
for those 35 + treatments vary from 3 to 18 months.
Your skin will continuously improve with ongoing use. Ongoing use of the dermal roller is
recommended for all ages. You will look so much younger and healthier than the people in
the same age group.
Is it hard to use?
No but to achieve optimal results the roller must be used consistently with the correct
technique
Is Salon Treatment Necessary?
No but you will achieve better results quicker with some salon treatments for a number of
reasons.
• The rolling tends be more thorough and comprehensive in the salon • Serums and masques are used in the salon treatment as well as the rolling and with the greater absorption achieved your skin will be absorbing the potent Gernetic creams and serums at an optimal level. Hyperpigmentation.
We recently received a newsletter from company that sells Dermal Rollers, not the
company we source ours from. They said that they had been hearing from some buyers of
their rollers that were achieving some great results with hyperpigmentation and were
surprised as they did not know the mechanism behind it as they were mainly focused on
wrinkle treatment.
We are not surprised with such results, rolling can have a positive effect on
hyperpigmentation and Melasma ( a dark skin discoloration that appears on sun-exposed areas of the face).

Hyperpigmentation is a difficult condition to treat due to the many variables that influence
the melanocyte (melanin-producing cells located in the bottom layer (the stratum basale) of the skin's epidermis).
Some influencing factors are
• The Endocrine System – hyperpigmentation / Melasma is often associated with
the female hormones estrogen and progesterone. It is especially common in pregnant women, women who are taking birth control pills (oral contraceptives) and women taking hormone replacement therapy (HRT) during menopause. Melasma is a very common skin disorder. Though it can affect anyone, young women with brownish skin tones are at greatest risk. • The functioning of the Keratinocyte (the predominant cell type in the epidermis,
the outermost layer of the human skin, constituting 95% of the cells found there) The functioning of the Fibroblast (a type of cell that synthesises the extracellular matrix and collagen
and elastin )
UV exposure. (particulary UVB)

The melanocyte can be damaged internally and externally leading to hyperpigmentation.
External damage can be in the form of UV exposure which causes the melanocyte’s
Dendrites (nueral branches) to become shortened resulting in increased pigment
deposition in Keratinocytes close the the mealocyte itself. Internal damage can be in the
form of Mitochondrial damage (Mitochondria are the cell's power producers. They convert energy into forms that
are usable by the cell). Some other causes / triggers are
Drugs such as (anti –epileptic, anti – depressants, antibiotics, malaria drugs, diuretics, Doxorbicin) Post inflammatory reactions – (eg) Acne, Burns, Insect bites) • Cellular senescence (an aged cell that has forgotten how to function). • Photosensitisers (eg) some essential oils, particularly the citrus family, fragrances How Can Skin Rolling Help All This?
Skin rolling can help because
• It increases the availability of skin lightening actives • It helps to restore keratinocyte function (1) improves signalling between the outer layer skin cells and the melanocyte cell (2) normalises keratinocyte function to optimise pigment uptake. • Restores fibroblast function which normalises cell cross talk with the melanocyte. • Normalises the dendrite function of the melanocyte which regulates a protein (kinase). Increased levels of this protein lead to increased levels of pigment in UV exposed cells. If you have any further questions on this or any skin care concerns please feel
free to contact us at Human Nurture.

Source: http://www.blushzuidas.nl/bestanden/thuisroller-BLUSH.pdf