organized by the
ROMANIAN SOCIETY OF ALLERGOLOGY AND CLINICAL IMMUNOLOGY (RSAIC)
The 6th Balkan Congress of Immunology of BAIS
organized by the
BALKAN ASSOCIATION OF IMMUNOLOGICAL SOCIETIES (BAIS)
28 April – 1 May 2010, Sibiu, Romania
BALKAN ASSOCIATION OF IMMUNOLOGICAL SOCIETIES (BAIS)
ROMANIAN SOCIETY OF ALLERGOLOGY AND CLINICAL IMMUNOLOGY (RSACI)
Diana Deleanu (Romania), President of RSACI Dorel Lucian Radu (Romania), President of RSI Gunnur Deniz (Turkey), President of BAIS Miodrag Colic (Serbia) Mirko Spiroski (Macedonia) Snejina Nikolova Marinova (Bulgaria) M. Varla-Lefterioti (Greece) Victor Cristea (Romania) Gina Manda (Romania) Cristiana Matache (Romania) Ana Calugaru (Romania) Crina Stavaru (Romania) Aurora Salageanu (Romania) Monica Neagu (Romania) Poliana Leru (Romania) Florin Dan Popescu (Romania) Codrut Sarafoleanu (Romania) Georgeta Siniski (Romania) Ioana Agache (Romania) Corina Ureche (Romania) Ioan Bradu Iamandescu (Romania) Corina Porr (Romania) Loredana Piloff (Romania) Daniela Muti (Romania) 28 April – 1 May 2010, Sibiu, Romania
BALKAN ASSOCIATION OF IMMUNOLOGICAL SOCIETIES (BAIS)
The 6th Balkan Congress of Immunology of BAIS
28 April – 1 May 2010, Sibiu, Romania RAMADA Hotel 16.00: Registration of participants – registration desk, 1st floor 17.00 – 17.30: Press Conference
„INTERNATIONAL DAY OF ALLERGY (28 April) and DAY OF IMMUNOLOGY (29 April)“
17.30 – 18.00: Conference Opening Speakers:
Diana Deleanu (Romania) – President of SRAIC
Yldiz Camcioglu (Turkey) – BAIS Representative
D. L. Radu (Romania) – President of SIR
Jose Rosado Pinto (Portugalia): THE FUTURE OF ALLERGOLOGY IN EUROPE Guests of Honour: Klaus Johannis, Mayor of Sibiu Ioan Manitiu, Manager, Direction of Health, Sibiu County Radu Chicea, President of the College of Physicians, Sibiu County
19.00: Welcome Cocktail offered by GSK – Centrum Bar, ground floor
BAIS Conference: „DAY OF IMMUNOLOGY – DOI 2010“ Chairpersons: D. L. Radu, Ana Calugaru, (Romania) M. Varla-Leftherioti (Greece) Plenary lectures 9.00 – 9.30 PL 1 Roche: IMMUNOLOGICAL APPLICATION FOR XCELLIGENCE SYSTEM – Bill Cigich (USA) 9.30 – 10.30 PL 2: TUMOR IMMUNOTHERAPEUTIC STRATEGIES USING NOVEL IMMUNOMODULATORS – Ourania Tsitsilonis (Greece) 10.30 – 11.00: Coffee break 11.00 – 12.00 PL 3: THE ROLE OF KIR-HLA INTERACTIONS IN ALLOGENEIC AND ANTI-TUMOR REACTIONS – M. Varla-Leftherioti (Greece) 12.00 – 13.00 PL 4: THE IMMUNE PARADOX OF PREGNANCY – Chrissa Papasteriades (Greece) 13.00 – 14.00: Lunch BAIS CONFERENCE DAY OF IMMUNOLOGY – DOI 2010 Chairpersons: V. Cristea, E. Carasievici (Romania) 14.00 – 15.00 PL 5: IMMUNOREGULATORY MECHANISMS IN CHRONIC INFLAMMATION – 15.00 – 15.30 PL 6: THERAPEUTICAL STRATEGIES IN DIABETES TYPE 1 – D.L. Radu (Romania) 15.30 – 16.30 Oral presentations CELLULAR RECEPTORS AND MARKERS (I) Chairpersons: Ourania Tsitsilonis (Greece), Monica Neagu (Romania) I 1 ADIPOKINES AND BONE SPECIFIC ACTIVITY SURROGATES IN CHRONIC HEART FAILURE:
Biljana Bozic, Goran Loncar, Nenad Prodanovic, Zoran Radojicic, Vojkan Cvorovic, Sinisa Dimkovic, VeraPopovic-Brkic (Serbia)
I 2 ASSOCIATION OF TLR-7 EXPRESSION WITH FUNCTIONAL AND PHENOTYPIC PROPERTIES OF LOXORIBINE-TREATED MONOCYTE-DERIVED DENDRITIC CELLS: Tanja Dzopalic, Ana Dragicevic, Sasa Vasiljic, Dragana Vucevic, Miodrag Colic (Serbia) I 3 IMMUNOMODULATORY PROPERTIES OF HUMAN DENTAL MESENCHYMAL STEM CELLS: Ser-
gej Tomic, Jelena Djokic, Sasa Vasilijic, Dragana Vucevic, Vera Todorovic and Miodrag Colic (Serbia)
16.00 – 16.30: Coffee break 16.30 – 18.00 Oral presentations AUTOIMMUNITY (II) Chairpersons: E. Nagy, Cristiana Matache (Romania) SEMAPHORIN 4D AND ITS RECEPTOR CD72 MEDIATE SOME ABNORMALITIES IN HUMAN AUTOIMMUNE DISEASES: Alina Besliu, Leontina Banica, Gina Pistol, Denisa Predeteanu, Ruxandra Ionescu, Violeta Vlad, Maria Stefanescu and Cristiana Matache (Romania)
VITAMIN D EFFECT ON REGULATORY T CELLS: Leontina Mirela Banica, Gina Pistol, Alina Nicoleta Besliu, Denisa Predeteanu and Cristiana Matache (Romania) DETERMINATION OF MATRIX METALLOPROTEINASE-8 AND TNFα IN SERUM AND SYNOVIAL FLUID OF KNEE OSTEOARTHRITIS PATIENTS: Elöd Nagy, Edina Láng, István Gergely, Örs Nagy (Romania) DOUBLE TRANSGENIC MICE WITH TYPE 1 DIABETES – A STUDY MODEL OF DIABETIC NEU- ROPATHY: Iancu Adina Daniela, Radu Beatrice Mihaela, Radu M., Stavaru Crina, Radu D.L. (Romania) GENERATION OF GENE-ENGINEERED CHIMERIC DNA MOLECULES BY RECOMBINANT TECH- NOLOGIES FOR SPECIFIC THERAPY OF AUTOIMMUNE DISEASES: Andrey Tchorbanov, Vera Gesheva and Nikola Kerekov (Bulgaria) ELIMINATION OF DISEASE-ASSOCIATED B LYMPHOCYTES BY CHIMERIC MOLECULES IN SCID MODEL OF MOUSE LUPUS: Vera Gesheva, Nikola Kerekov, Kalina Nikolova, Nikolina Mihaylova, Todor Todorov, Maria Nikolova and Andrey Tchorbanov (Bulgaria) AUTOIMMUNE MODIFICATIONS, LOCAL AND SYSTEMIC, IN RHEUMATOID ARTHRITIS: Ramona Cioaca, Ioana Ionita, Claudiu Ionita, Adina Bucur, Hortensia Ionita, V. Paunescu (Romania) PATHOLOGIC MONOCYTES IN RHEUMATOID ARTHRITIS: Gina Manda, Ionela Victoria Neagoe, L. Albulescu, Carolina Negrei, Lacramioara Popa (Romania) IGE-MEDIATED IMMUNE RESPONSE IN CELIAC DISEASE TO THE CHILD: Samasca G., Dejica D. (Romania) II 10 HELPER AND REGULATORY T-LYMPHOCYTE EVALUATION DURING BIOLOGIC AND IMMUNOSUPPRESSIVE THERAPY FOR RHEUMATOID ARTHRITIS: C. Ursaciuc, Mihaela Surcel, R. Huica, D. Ciotaru, Ioana Ruxandra Pirvu, Carmen Ardeleanu, Georgeta Butur, Denisa Predeteanu, Maria Dobre, Silvia Sorca (Romania) 18.00 – 19.00 Poster presentations RECEPTORS AND MARKERS (A) AUTOIMMUNITY (B) Chairpersons: C. Ursaciuc, Ramona Cioaca (Romania) CANTASTIM ACTIVATES HUMAN MACROPHAGES BY INTERACTION WITH TOLL-LIKE RECEPTOR 2: Iuliana Caras, Catalin Tucureanu, Ramona Pitica, Lucian Lerescu, Adrian Onu, Aurora Salageanu (Romania) A 2 HUMAN MONOCYTIC LEUKEMIA CELL LINE THP-1 AS A MODEL FOR STUDYING ACTIVATION OF TOLL-LIKE RECEPTORS: Ramona Pitica, Iuliana Caras, C. Tucureanu, L. Lerescu, Aurora Salageanu (Romania) A 3 PERIPHERAL BLOOD CD8 T CELL RESPONSES IN PATIENTS WITH ACTIVE TB, RECENT CONTACTS, AND HIGHLY EXPOSED HEALTHCARE WORKERS: M. Nikolova, M. Muhtarova, A. Mihova, R. Drenska, R. Markova, V. Dimitrov, M. Amicossante, H. Taskov (Bulgaria) A 4 STUDY OF NON-INVASIVE MARKERS FOR DIAGNOSIS AND PROGNOSIS OF NON-ALCO- HOLIC STEATO-HEPATITIS: Maria Dobre, D. Ciotaru, Mihaela Surcel, Ioana Ruxandra Pîrvu, R. Huica, Gheorghita Isvoranu, L. Micu, I. Copaci, C. Ursaciuc (Romania) A 5 HIGHLY INCREASED LEVELS OF TUMOR NECROSIS FACTOR-ALPHA AND OTHER PROIN- FLAMMATORY CYTOKINES IN MULTIPLE MYELOMA: Ioana Ionita, Gabriela Ramona Cioaca, Claudiu Ionita, Adina Bucur, Hortensia Ionita (Romania) A 6 SCREENING OF CYTOTOXIC ANTIBODIES FOR THE RENAL TRANSPLANT: Elena Gai, Alexan-
dra Gruia, Florina Boldeanu, Florina Bojin, C.Tatu, O. Golea, Anca Mates, V. Paunescu (Romania)
A 7 FUNCTIONALLY CARACTERISTICS OF ENDOTHELIAL-LIKE CELLS OBTAINED BY DIFFEREN- TIATION OF HUMAN HEMATOPOIETIC STEM CELLS: Daciana Nistor, Ioana Siska, Carmen Bunu, Gabriela Tanasie, Carmen Tatu, Florina Bojin, V. Paunescu (Romania) A 8 REESTABLISHING TOLERANCE TO DNA IN HUMANIZED MURINE MODELS OF SLE: Kerekov
N, Nikolova K, Mihaylova N, Tchorbanov A (Bulgaria)
A 9 THE CORRELATION CEA-CA72-4 IN DIGESTIVE ILLNESSES: Adriana Turculeanu, Maria Bala -
noiu, Reanina Ionescu, Anca Ungureanu, Carmen Avramescu, Mariana-Alina Sorescu (Romania)
A 10 CYTOTOXIC AND IMMUNOMODULATOY EFFECTS OF GOLD NANOPARTICLES PREPARED BY ULTRASONIC SPRAY PYROLYSIS: Jelena Djokic1, Rebeka Rudolf2, Bernd Friedrich3, Srecko Stopic3, Ivan Anzel2, Sergej Tomic1, Sasa Vasilijic1, Miodrag Colic1,4 NEW THERAPEUTIC APPROACH FOR SELECTIVE SUPPRESSION FOR PATHOLOGICAL AUTOREACTIVE B LYMPHOCYTES: Kalina Nikolova, Vera Gesheva, Reinhard Voll and Tchavdar Vassilev (Bulgaria) PSORIATIC ARTHRITIS. RELATIONSHIP BETWEEN PROINFLAMMATORY STATUS AND ACTIVITY OF DISEASES: Camelia Ciacli, M. Cojocaru (Romania) THE CORRELATIONS BETWEEN AUTOANTIBODIES AND CYTOKINES IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): Isabela Silosi, M. Cojocaru, F. Petrescu, V. Biciusca, C.Silosi, Inimioara Mihaela Cojocaru, O. Zlatian, Ourania Drakoulogona, V. Padureanu, Alice Gaman (Greece and Romania) THE PREVALENCE OF AUTOANTIBODIES IN VIRAL CHRONIC HEPATITIS: Isabela Silosi, M. Cojocaru, V. Biciusca, Lucica Rosu, O. Zlatian, Ourania Drakoulogona, Inimioara Mihaela Cojocaru, C.Silosi, Alice Gaman, V. Padureanu (Greece and Romania) HUMAN MITOMYCIN C-TREATED DENDRITIC CELLS SUPPRESS ALLOGENEIC T-CELL RESPONSE IN-VITRO. AN EFFECT MEDIATED BY INDUCTION OF CD4+CD25+FOXP3+ TREGS.: Janina Jiga, L Jiga, B Hoinoiu, G Dindelegan, A. Blidisel, C Tatu, M Ionac, V. Paunescu (Romania) APOLIPOPROTEIN E (APO E) POLYMORPHISM IN GREEK PATIENTS WITH TYPE 2 DIABETES MELITUS (T2D): CORRELATION WITH DIABETIC MICRO- AND MACROANGIOPATHY: K. Tarassi, D. Kouniaki, G. Ioannidis, T. Athanassiades, G. Skalis, E. Papasteriadis, C. Papasteriades (Greece)
19.30: GALA Dinner offered by MSD – Atrium Restaurant
BAIS CONFERENCE Chairpersons: M. Colic (Serbia), P. Cianga (Romania) Plenary lectures 9.00 – 9.30 PL 7: INFLAMMATORY CANCER MICROENVIRONMENT – E. Carasievici (Romania) 9.30 – 10.00 PL 8: IMMUNE-RELATED BIOMARKERS IN SKIN MELANOMA – Monica Neagu 10.00 – 10.30 PL 9: TRICHINELLA ANTIGENS AS POWERFUL MODULATORS OF IMMUNE RESPONSE – Ljiljana Sofronic-Milosavljevic (Serbia) 10.30 – 11.00: Coffee break 11.00 – 12.30 Oral presentations TUMORAL IMMUNOLOGY (III) Chairpersons: E. Carasievici, Lorelei Brasoveanu (Romania) III 12 TUMOR-ASSOCIATED FIBROBLASTS AS A FUNCTIONAL IMMUNOSUPPRESSIVE NETWORK IN CANCER DEVELOPMENT: V. Paunescu, Florina Bojin, Calin A., Tatu, Oana Gavriliuc, Adriana Rosca, Gabriela Tanasie, Carmen Bunu (Romania) III 13 MCF-7 AND SK-BR3 CELLS DISPLAY DIFFERENT RESPONSES TO TNFα, TNFβ, GPR30 AGONIST AND TAMOXIFEN: Petru Cianga, Corina Cianga, Eugen Brailoiu (Romania) III 14 BIOMARKERS ASSOCIATED TO COLON CANCER CELLS – POTENTIAL IMMUNOTHERAPEU- TICAL TARGETS: Lorelei Irina Brasoveanu, Camelia Hotnog, I. Dina, Mirela Mihaila (Romania) III 15 COMPLEX COMBINATIONS WITH MACROCYLIC LIGANDS – AN IN VITRO APPROACH ON TUMOR CELL LINES: Constantin Carolina, Boscencu Rica, Ilie Mihaela, Socoteanu Petre, Neagu Monica (Romania) III 16 INHIBITION OF INDUCED MOUSE B16 MELANOMA BY COPPER MICROSPHERICAL PARTI- CLES: Ana Calugaru, Cristina Surdu Bob, Lidia Cremer, M. Badulescu, C. Coman (Romania) III 17 PRELIMINARY STUDY OF BASELINE BREATHING PARAMETERS IN ADULT MICE BY WHOLE BODY PLETHYSMOGRAPHY: Rasid O., Iancu Adina Daniela, Radu D.L., Stavaru Crina (Romania) III 18 BLOOD ANGIOGENIC PROFILE FOR THE EARLY DETECTION OF PROSTATE CANCER. A PILOT STUDY: Ovidiu Balacescu, Oana Tudoran, N.Crisan, Loredana Balacescu, Claudia Burz, V. Cristea, Ioana Berindan-Neagoe (Romania) III 19 NK CELL SUBPOPULATIONS IN METASTATIC CANCER: C. Ursaciuc, Mihaela Surcel, D. Ciotaru,
R. Huica, Maria Dobre, Ioana Ruxandra Pîrvu, E. Bratucu, C. Cirimbei, D. Mischianu, O. Bratu,Gheorghita Isvoranu
12.30 – 13.30 Oral presentations ANTINFECTION IMMUNITY (IV) Chairpersons: Ljiljana Sofronic-Milosavljevic (Serbia), Gina Manda (Romania) IV 19 EXPERIMETAL MURINE MODELS OF INFECTION WITH STREPTOCOCCUS PYOGENES AND CELLULAR IMMUNE RESPONSE: Iancu Adina Daniela, Pana Marina, Radu D.L. (Romania) IV 20 INDUCTION AND DEVELOPMENT OF BRONCHO-ASSOCIATED LYMPHOID TISSUE (BALT) AFTER INTRANASAL IMMUNIZATION AND REIMMUNIZATION WITH BCG VACCINE: Milena Bachvarova, Sasha Nikolaeva (Bulgaria) IV 21 COMPARATIVE STUDY OF INFLUENZA VACCINE IMMUNOGENICITY: Stavaru Crina, Lupulescu
Emilia, Coman C, Rasid O, Iancu Adina Daniela, Baetel Alina, Necula G, Ionita E, Berbecila L, VlaseE, Alexandrescu V, Mazilu Margareta, Radu D.L, Onu A. (Romania)
IV 22 EXPOSURE OF IgG TO AN ACIDIC ENVIRONMENT RESULTS IN MOLECULAR MODIFICA- TIONS AND IN ENHANCED PROTECTIVE ACTIVITY IN SEPSIS: Iglika K. Djoumerska-Alexieva, Jordan D. Dimitrov, Elisaveta N. Voynova, and Tchavdar L. Vassilev (Bulgaria) 13.30 – 14.30: Lunch 14.30 – 15.30 Poster presentations TUMORAL IMMUNOLOGY (C) Chairpersons: Aurora Salageanu, Crina Stavaru (Romania) PROTEOMIC APPROACHES FOR BIOMARKER DISCOVERY IN DIGESTIVE CANCER: Tanase C., Albulescu R., Popescu ID., Albulescu L., Raducan E., Codorean E., Petrutescu M., Simion S. (Romania) PERIOPERATIVE IMMUNE PROFILE IN CANCER PATIENTS: C. Tucureanu, Iuliana Caras, L. Lerescu, Laura Melinceanu, Ramona Pitica, R. Costea, G. Gangura, St. Neagu, C. Sarafoleanu, Aurora Salageanu (Romania) EFFECTS OF TRASTUZUMAB TREATMENT ON ERBB2 EXPRESSION, APOPTOSIS AND CELL CYCLE CHANGES IN LARYNGEAL CANCER: Marinela Bostan, Georgiana Gabriela Matei, Mirela Mihaila, D. Manu (Romania) RELATIONSHIP BETWEEN HLA A*02 ALLELE AND THE RISK OF CHILDHOOD ACUTE LEUKE- MIA: Elena Gai, Alexandra Gruia, Florina Boldeanu, Margit Serban, Simona Arghirescu, C. Jinca, C. Tatu, Loredana Balint Gib, V. Ordodi, V. Paunescu (Romania) THE EFFECT OF TRICHINELLA SPIRALIS EXCRETORY-SECRETORY ANTIGEN ON B16 MELA- NOMA CELLS IN VITRO: Jelena Cvetkovic, S. Vasilev, M. Colic, Ivana Majstorovic, Zorica Juranic, Natasa Ilic, Alisa Gruden-Movsesijan, Ljiljana Sofronic-Milosavljevic (Serbia) FUNCTIONAL STUDIES ON NORMAL AND TUMORAL CELLS EXPOSED TO DIFFERENT CONCENTRATIONS OF ARISTOLOCHIA CLEMATITIS AQUEOUS EXTRACTS: Mirabela Cristea, Alexandra Gruia, Florina Bojin, Elena Gai, Oana Gavriliuc, Adriana Rosca, Simona Anghel, C.Tatu, V. Paunescu (Romania) IMMUNOPHENOTYPIC CHARACTERIZATION OF SEVERAL TUMORAL CELL LINES AND CYTOTOXICITY EVALUATION OF CERTAIN ANTITUMORAL COMPOUNDS BY ALAMAR BLUE ASSAY: Alexandra Gruia, Florina Bojin, Mirabela Cristea, V. L. Ordodi, Oana Gavriliuc, Elena Gai, Simona Anghel, Adriana Rosca, C. Tatu, V. Paunescu (Romania) ENHANCEMENT OF SOME CYTOSTATIC DRUGS ACTIVITY ON TUMOR CELL LINES USING CURDLAN DERIVATIVES: Mihaela Badulescu, Natalia Simona Apetrei, Lidia Cremer, Andreea Lupu, M. Moscovici, Georgeta Mocanu, Doina Mihai, G. Szegli, Ana Calugaru (Romania) EXPERIMENTAL MODEL ON HUVEC ENDOTHELIAL CELL LINE TO STUDY VARIOUS CYTOKINES INVOLVEMENT IN TUMOR GROWTH AND REGRESSION: D. Ciotaru, Mihaela Sur- cel, Maria Dobre, Ioana Ruxandra Pîrvu, R. Huica, Gheorghita Isvoranu, Adriana Diaconeasa, D. Boda, C. Ursaciuc (Romania) C 10 ADIPOCYTES-INDUCED CHANGES IN TUMOR MICROENVIRONMENT AND CANCER CELLS BEHAVIOR: Bojin Florina, Tatu C, Gavriliuc Oana, Boleman Alexandra, Gruia Alexandra, Cristea Mirabela, Anghel Simona, Nistor Daciana, Tatu Carmen, Tanasie Gabriela, Bunu Carmen, Paunescu V. (Romania) C 11 MODULATION OF CELL PROLIFERATION AND APOPTOSIS IN CERVICAL CANCER: Lorelei Irina
Brasoveanu, Camelia Hotnog, Irina Huica, Mirela Mihaila, Gabriela Anton (Romania)
C 12 ANALYSIS OF CELL CYCLE PROGRESSION AND CELL GROWTH AFTER GENISTEIN TREAT- MENT IN B CELL CHRONIC LYMPHOCYTIC LEUKEMIA: Dan Hotnog, Viviana Roman (Romania) 15.30 – 16.30 Plenary lecture (PL 10): CYTOKINES MOLECULAR MEDIATORS OF IMMUNE RESPONSE – V. Cristea (Romania) 16.30 – 17.00: Coffee break 17.00 – 18.00 Oral presentations ALLERGOLOGY (VI) Chairperson: V. Cristea (Romania) VI 24 CLINICAL AND IMMUNOLOGICAL CORRELATIONS IN CHILDHOOD ASTHMA: Muti A.D., Iacob
D., Farcau M., Ilies O., Panaete A., Cretu D., Gherman P. (Romania)
VI 25 BRONCHO-OBSTRUCTIVE SYNDROME IN CHILDHOOD – IS IT ALWAYS ASTHMA?: Iacob D.,
Muti A.D., Farc`u D., Fufezan O. (Romania)
18.00 – 19.00 Poster presentations ANTIINFECTION IMMUNITY (D) ALLERGOLOGY (E) VARIA (F) Chairpersons: Lucica Rosu, Edith Szekely (Romania) D 1 COMPARISON OF EFFECTS OF ORAL POLYBACTERIAL IMMUNOMODULATORS ON HUMORAL SYSTEMIC AND MUCOSAL IMMUNITY IN PATIENTS: R. Kostadinova-Yankova, P. Nenkov, B. Petrunov, S. Marinova (Bulgaria) AUTOANTIBODIES AND TRICHINELLA SPIRALIS ANTIGENS: Ivana Radovic, Alisa Gruden-Movsesi- jan, Natasa Ilic, Marija Mostarica-Stojkovic, Ljiljana Sofronic-Milosavljevic (Serbia) D 3 RESTORATION OF PATIENTS WITH FOCAL ORAL INFECTION CORRELATES WITH HIGH PERIPHERAL BLOOD LEVELS OF IL-10, IL-4, IL-2 AND CD25HICD127LOW T REGULATORY CELLS: Draganka Stankulova, Mariana Cekova, A.Mihova, Angelina Kisselova, Hristo Taskov, Maria Nikolova (Bulgaria) D 4 IMMUNOSUPPRESSION AND THE INFECTION WITH VARICELLA-ZOSTER VIRUS: Emilia
Nicoara, A. Crisan, Ruxandra Laza (Romania)
D 5 IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME (IRIS) PRODUCING ATYPICAL PRESENTATIONS OF „OPPORTUNISTIC” MENINGOENCEPHALITIS REACTIVATION: Virgil Musta, Melania Oana, Emilia Nicoara, Teodora Moisil, Georgeta Cornea (Romania) D 6 IMMUNOSUPPRESSION IN HIV – CONTRIBUTING FACTOR FOR FUNGAL INFECTIONS:
Narcisa Nicolescu, Emilia Nicoara, Karina Bota, A. Crisan, Daniela Desaga (Romania)
D 7 THE ROLE OF IMMUNE INVESTIGATION IN MANAGEMENT OF TREPONEMA PALLIDUM INFECTION: Lucica Rosu, Sorina Comisel, O. Zlatian, Georgiana Sireteanu, Aurelia Teodorescu, Irina Stoicescu, Alexandra Floriana Rosu (Romania) D 8 CORRELATION BETWEEN FEMALE INFERTILITY AND CHLAMYDIAL INFECTION: Lucica Rosu,
Sorina Comisel, O. Zlatian, Georgiana Sireteanu, Andreea Ilie, Irina Stoicescu, Alexandra FlorianaRosu (Romania)
TREATMENT OF ALLERGEN-SPECIFIC B LYMPHOCYTES WITH CHIMERIC PROTEIN-ENGINEERED MOLECULES: A. Michova, M. Nikolova, G. Nikolov, M. Muhtarova, V. Gesheva, N. Kerekov, A. Tchorbanov, B. Petrunov (Bulgaria) TRANS-DISCIPLINARY LINKS BETWEEN MOLECULAR BIOLOGY, EPIDEMIOLOGY AND IMMUNOLOGY: Alina Orasteanu, Irina Negoescu, Cecilia Galatiuc (Romania)
9.30: Participations Award CONCLUDING REMARKSRSI GENERAL ASSEMBLY
ROMANIAN SOCIETY OF ALLERGOLOGY AND CLINICAL IMMUNOLOGY (RSACI) 28 April – 1 May 2010, Sibiu, Romania RAMADA Hotel 16.00: Registration of participants – registration desk, 1st floor 17.00 – 17.30: Press Conference
„INTERNATIONAL DAY OF ALLERGY (28 April) and DAY OF IMMUNOLOGY (29 April)“
17.30 – 18.00: Conference Opening Speakers:
Diana Deleanu (Romania) – President of SRAIC
Yldiz Camcioglu (Turkey) – BAIS Representative
D. L. Radu (Romania) – President of SIR
Jose Rosado Pinto (Portugalia): THE FUTURE OF ALLERGOLOGY IN EUROPE Klaus Johannis, Mayor of Sibiu Ioan Manitiu, Manager, Direction of Health, Sibiu County Radu Chicea, President of the College of Physicians, Sibiu County
19.00: Welcome Cocktail offered by GSK – Centrum Bar, ground floor
8.30 – 9.30 Workshops (W) HYMENOPTERA ALLERGY Chaiperson: Diana Deleanu (Romania) W 1 IMMUNOTHERAPY IS THE ONLY SPECIFIC TREATMENT FOR PATIENTS WITH SYSTEMIC REACTIONS TO HYMENOPTERA STING ALLERGY: Diana Deleanu (Romania) W 2 HYMENOPTERA ALLERGENS: Daniela Muti, Diana Deleanu (Romania) W 3 LIVING INSECT CHALLENGE TEST: Adriana Bujor, Diana Deleanu (Romania) 9.30 – 10.00 Plenary lecture PL1: CONTEMPORARY MAN, THE “GREENHOUSE EFFECT” AND THEIR IMPACT ON ALLERGENS AND THE PRACTICE OF ALLERGOLOGY – Kalliopi Kontu-Filli (Grecia) 10.00 – 10.30: Coffee break 10.30 – 11.00 Plenary lecture PL 2: GENE AND ENVIRONMENT INTERACTIONS IN ASTHMA: Omer 11.00 – 11.30 Plenary lecture PL 3: NEW INSIGHTS IN THE IMMUNOLOGICAL BACKGROUND OF ATOPIC ALLERGY – Martien Kapsenberg (Olanda) 11.30 – 12.30 GSK Symposium: LATEST DEVELOPMENTS IN PAEDIATRIC ASTHMA Speaker: Doina Plesca (Romania) WELCOME TO A WORLD OF RELIEF FOR NOSES AND EYES Speaker: Diana Deleanu (Romania) 12.30 – 13.00 Danone Symposium: PROBIOTIC YOGHURTS: FROM NATURAL, TRADITIONAL FOOD TO FUNCTIONAL FOOD Speakers: Diana Deleanu, Julieta Cristescu (Romania) 13.00 – 14.00: Lunch 13.00 – 14.00 Poster presentations VARIA (VA) VA 1 ORAL ALLERGIC SYNDROME – A CASE REPORT: Corina Porr, Paul Jurgen Porr (Romania) VA 2 CHRONIC GENERALIZED SEVERE URTICARIA – A CASE REPORT: Corina Porr, Paul Jurgen Porr, VA 3 CLINICAL AND IMMUNOLOGICAL CORRELATIONS IN CHILDHOOD ASTHMA: Muti A.D., Iacob
D., Farcau M., Ilies O., Panaete A., Cretu D., Gherman P. (Romania)
VA 4 BRONCHO-OBSTRUCTIVE SYNDROME IN CHILDHOOD – IS IT ALWAYS ASTHMA?: Iacob D.,
Muti A.D., Farcau D., Fufezan O. (Romania)
VA 5 TWO CASE OF STEVENS-JOHNSON SYNDROME: Andreea Csillag1, László Gyula Fekete,
Carmen Friciu, Alexandrina Ionita, Dumitru Moldovan (Romania)
14.00 – 16.00 Oral presentations DRUG ALLERGY (I) Chairpersons: Nadia Gherman Ionica, Natalia Hagau (Romania) DRUG INDUCED ANAPHYLAXIS- DIAGNOSIS AND TREATMENT: Natalia Hagau, Nadia Gherman-Ionica, Ramona Bologa (Romania) NEW INSIGHTS IN NEUROMUSCULAR BLOCKING AGENTS (NMBA) HYPERSENSITIVITY REACTIONS: Nadia Gherman-Ionica, Natalia Hagau, Ramona Bologa, Corina Jurc` (Romania) UPDATES IN THE DIAGNOSIS OF IMMEDIAT ANTIBIOTICS ALLERGY: Ramona Bologa, Nadia Gherman-Ionica, Natalia Hagau (Romania) DIAGNOSIS OF ADVERSE REACTIONS ASPIRIN/NSAID-INDUCED: Camelia Berghea, Nadia Gherman-Ionica (Romania) IMMUNE DRUG REACTIONS: Ioana Agache (Romania) 16.00 – 16.30: Coffee break 16.30 – 18.00 Oral presentations ALLERGIC RHINITIS (II) Chairperson: Codrut Sarafoleanu (Romania)
Introduction – Allergic rhinitis in ENT practice: Codrut Sarafoleanu (Romania) DIFFERENTIAL DIAGNOSIS OF ALLERGIC RHINITIS: Ioana Pedestru (Romania) DIAGNOSIS OF ALLERGIC RHINITIS – THE ENT SPECIALIST PERSPECTIVE: Claudiu Manea, Isabela Lupu, Neli Banesaru (Romania) THE SYMPTOMATIC TREATMENT OF ALLERGIC RHINITIS: Sorin Sabau (Romania) THERAPEUTIC OPTIONS IN ALLERGIC RHINITIS: Codrut Sarafoleanu, Raluca Enache, Andra Savu (Romania) ALLERGIC RHINITIS IN CHILDREN: Boris Smoc (Romania) II 6 SURGICAL TREATMENT OF ALLERGIC RHINITIS: George Mincu (Romania) 16.30 – 17.30 Oral presentations ASTHMA MANAGEMENT (III) Chairperson: Ioana Agache III 1 OXIDANTS AND ANTIOXIDANTS SYSTEMS IN CHILDREN WITH ASTHMA: Omer Kalayci III 2 COMPLEMENTARY AND ALTERNATIVE MEDICINE IN ASTHMA – WHERE ARE WE: Ioana III 3 NEW ASTHMA THERAPIES: Corina Ureche (Romania) 18.00 –18.30 Allergodil Symposium: AZELASTINE – PROMPT AND LONGLASTING IMPACT ON ALLERGY SYMPTOMATOLOGY Chairperson: Diana Deleanu 1 Topic Antihistamine Treatment in Allergic Rhinitis / Rhinoconjunctivits: Codrut 2 Azelastine Identity Within AR Treatment Guidelines: Larisa Leibersperger (Germania) 3 Azelastine: Interspeciality Alliance: Diana Deleanu (Romania) 18.30 – 19.30 MSD Symposium: DIFFERENT PATIENTS, DIFFERENT NEEDS A COMPLETE SOLUTION IN RESPIRATORY DISEASES Chairperson: Diana Deleanu 1 MODERN TREATMENT OF ALLERGIC RHINOCONJUNCTIVITIS; FROM EVIDENCE BASED MEDICINE TO CLINICAL PRACTICE: Ioana Agache STRATEGIC PARTNERSHIP FOR ASTHMA CONTROL: Dragos Bumbacea
19.30: GALA Dinner offered by MSD – Atrium Restaurant
8.30 – 9.00 Oral presentation RECENT ADVANCES IN EGG ALLERGY: Corina Ureche (Romania) 9.00 – 13.00 Oral presentations PAEDIATRIC ALLERGOLOGY (IV) Chairperson: Doina Plesca (Romania) IV 1 THE PREVALENCE OF ASTHMA IN CHILDREN IN ROMANIA: Cristian Gheonea (Romania) IV 2 COMORBIDITIES IN ASTHMA: Dumitru Orasanu (Romania) IV 3 EDUCATION OF ASTHMATIC CHILDREN: Jose Rosado Pinto (Portugalia) IV 4 THERAPEUTIC DILEMMAS IN WHEEZING IN PRESCHOOL CHILDREN: Doina Plesca, Victoria IV 5 HOW ALLERGIC IS THE ATOPIC CHILD?: Ioan Cernatescu (Romania) IV 6 IGE-MEDIATED IMMUNE RESPONSE IN CELIAC DISEASE TO THE CHILD: Gabriel Samasca, 10.30 – 11.00: Coffee break IV 7 ALLERGIC RHINITIS: Mircea Nanulescu, Diana Deleanu, Sorin Man, Silviu Albu (Romania) IV 8 ALLERGY TO COW’S MILK PROTEINS: Mihai Neamtu (Romania) IV 9 EOSINOPHILIC GASTROENTERITIS: Victoria Hurduc (Romania) IV 10 ATOPIC ECZEMA/DERMATITIS SYNDROME IN CHILD: Stela Gotia, Aurica Rugina (Romania) IV 11 URTICARIA AND ANGIOEDEMA: Alexandru Ierima (Romania) IV 12 IgE IN IMMUNE DISFUNCTIONS: CERTAINTIES, PRECAUTIONS AND PITFALLS: Evelina Moraru IV 13 DRUG ALLERGIES: Paraschiva Chersches Panta (Romania) 13.00 – 14.00: Lunch 13.00 – 14.00 Poster presentations VARIA (VA) VA 6 PRACTICAL PROBLEMS INVOLVED IN ANAPHYLACTIC SHOCK AT THE WHEEL WHILE DRIVING: Alexandru Chitu (Romania) VA 7 ALLERGIC ASTHMA TO DAPHNIA SP. – CLINICAL AND EPIDEMIOLOGICAL FINDINGS: Ioan
Bradu Iamandescu, Razvan Daniel Chivu (Romania)
SENSITIZATION TO RAGWEED POLLEN IN NORTH-WEST REGION OF ROMANIA: Bocsan Corina, Bujor Adriana, Barbanta Cristina (Romania) SUSCEPTIBILITY TO GENTAMICIN AMONG ESCHERICHIA COLI STRAINS IN URINARY ISOLATES FROM PATIENTS WITH DRUG HYPERSENSITIVITIES: Ionete Oana-Mariana, Greblescu Raluca, Popescu Florin-Dan (Romania) VA 10 THE RELATION BETWEEN SEVERE BRONCHIOLITIS AND BRONCHIAL ASTHMA IN CHILDREN:
Alina Murgu, Evelina Moraru, Aurica Rugina, Ileana Ioniuc, Tania Rusu, Paula Popovici (Romania)
VA 11 THE RELATION BETWEEN SEVERE BRONCHIOLITIS AND BRONCHIAL ASTHMA IN CHILDREN:
Alina Murgu, Evelina Moraru, Aurica Rugina, Ileana Ioniuc, Tania Rusu, Paula Popovici (Romania)
14.00 – 14.30 Workshop PRO AND CON IN SPECIFIC IMMUNOTHERAPY IN CHILDREN Chairperson: Mircea Nanulescu (Romania) Pro: Diana Deleanu (Romania) Con: Sorin Man (Romania) 14.30 – 16.30 CME Program CLINICAL EPIDEMIOLOGY AND EVIDENCE-BASED MEDICINE Chairpersons: Cristian Baicus, Poliana Leru (Romania) C 1 Types of clinical studies and expressing the risk. Evaluation of diagnostic test. Medical information: Cristian Baicus (Romania) C 2 Evaluation of a clinical study: Poliana Leru (Romania) 16.30 – 17.00: Coffee break 17.00 – 18.00 Plenary lecture (PL 4): PATHOGENESIS AND CLINICAL MANAGEMENT OF EYELID DERMATITIS – Andreas Wollenberg (Germania) 18.00 – 18.30 ASTRA ZENECA Symposium OVERALL ASTHMA CONTROL 8.30 – 9.00 Oral presentation NYCKEL – SENSITIZATION FACTOR IN ORAL PATHOLOGY – Georgeta Sini]chi 9.00 – 10.30 Oral presentations EDUCATION AND PSYCHOTHERAPY (V) Chairperson: Ioan Bradu Iamandescu (Romania) V 1 PSYCHO-SOCIAL BASIS OF EDUCATION OF ALLERGIC PATIENS: Ioan Bradu Iamandescu (Romania) V 2 QUALITY OF LIFE – EDUCATIONAL AND PSYCHOTHERAPEUTICAL OBJECTIVES IN ALLERGIC DISEASES: Alexandra Mihailescu, Ioan Bradu Iamandescu (Romania) V 3 THE SOCIAL COSTS CAUSED BY LOWADHERENCE TO TREATMENT AND INAPPROPRIATE EDUCATION OF ALLERGIC PATIENTS: Razvan Chivu, Ioan Bradu Iamandescu, Simona Coleasa (Romania) V 4 ROMANIAN VERSION OF JUNIPER ASTHMA QUALITY OF LIFE QUESTIONNAIRE: Alexandra V 5 ANXIETY DISORDERS AMONG ASTHMATICS. SOURCES. PSYCHOTHERAPEUTIC AND PSYCHOPHARMACOLOGIC TREATMENT: Mihaela Luminita Staicu (Romania) V 6 COGNITIV-BEHAVIORAL PSYCHOTHERAPY IN BRONCHIAL ASTHMA TREATAMENT: Daniela 10.30 – 11.00: Coffee break 11.00 – 12.00: Workshops (W) CYTOKINES – ARE THEY A SENSITIVE ENOUGH SENSOR FOR DIAGNOSIS AND TREATMENT? Chairpersons: Victor Cristea, Doru Dejica (Romania) W 4 CYTOKINES IN PARODONTAL DISEASE: Victor Cristea, Daniela Muti, Lucian Besa (Romania) W 5 PROINFLAMMATORY CYTOKINES AS POSSIBLE THERAPEUTIC TARGETS IN RHEUMATOID ARTHRITIS (RA): Doru Dejica (Romania) W 6 THE ROLE OF CYTOKINES IN MALIGNANT TUMORS: Ioana Berindan Neagoe, Claudia Burz, Ovidiu
Balacescu, Loredana Balacescu, Oana Tudoran, Cornelia Braicu, Alexandru Irimie, Victor Cristea(Romania)
W 7 CHEMOKINES IN TRANSPLANTATION: Claudia Burz, Ioana Neagoe, Daniela Muti, Leon Muti, W 8 TUMOR NECROSIS FACTOR α IN ASTHM: Adriana Bujor, Diana Deleanu, Victor Cristea (Romania) W 9 THE ANTIINFLAMMATORY EFFECT OF H1 ANTIHISTAMINES IN ALLERGIC RHINITIS: Corina W 11 THE ROLE OF CXCL10 IN THE PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS: W 10 CYTOKINES IN IMMUNODEFICIENCIES: Daniela Muti, Nadia Gherman-Ionica, Claudia Burz, Leon W 12 ADVERSE REACTIONS TO BIOLOGICAL AGENTS: Nadia Gherman-Ionica, Daniela Muti, Victor
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DERMATITIS ATÓPICA ¿Qué es la Dermatitis Atópica? Es una enfermedad inflamatoria de la piel, de tipo alérgico de curso crónico y recidivante, que se caracteriza por el desarrollo de lesiones de eczema con una distribución característica. La causa exacta es desconocida, cursa en brotes y se caracteriza por la presencia de eritema, sequedad cutánea y prurito intenso, lo q