Tadalafil entfaltet seine Wirkung über eine selektive Hemmung der PDE5, wodurch die Konzentration von cGMP im glatten Muskelgewebe stabil bleibt. Diese biochemische Modulation resultiert in einer langanhaltenden Relaxation der Gefäßwände. Der Wirkstoff wird nach oraler Einnahme effizient resorbiert, mit einer Bioverfügbarkeit von rund 80 %. Seine Halbwertszeit von bis zu 36 Stunden ist innerhalb dieser Substanzklasse außergewöhnlich. Abgebaut wird er in der Leber, hauptsächlich durch CYP3A4, mit anschließender biliärer Exkretion. Typische unerwünschte Wirkungen entstehen durch eine verstärkte Vasodilatation, etwa Kopfschmerzen oder Flush. Pharmakologisch wird cialis generika vor allem durch die verlängerte Wirkungsdauer charakterisiert.
Harris 2014-01-27 short.pdf
JOSHUA HARLAN HARRIS 74 Town Green Drive, Elmsford, NY 10523 • 646-660-0868 • joshuaharris@joshuaharris.org LEGAL EXPERIENCE Loeb & Loeb, L.L.P., New York, NY Morgan & Finnegan, L.L.P., New York, NY Associate, January 2009 to present Student Associate / Associate, June 2003 to January 2009
LITIGATION
• Writing successful briefs on motions for summary judgment and preliminary injunction, supporting
claim construction, seeking expert disqualification, and opposing production of privileged materials.
• Successfully arguing motions in United States District Court. • Negotiating terms of stipulated preliminary injunctions, confidentiality disclosure orders. • Preparing inventors, Rule 30(b)(6) witnesses, and other fact witnesses for deposition. • Preparing expert witnesses to testify at deposition and in United States District Court. • Taking and defending depositions of fact witnesses, Rule 30(b)(6) designees, and expert witnesses. • Engaging in pre-suit diligence, preparing complaints and responsive papers. COUNSELING AND DUE DILIGENCE
• Searching prior art and rendering patent infringement, validity, freedom to use opinions. • Auditing client patent portfolios to craft IP strategy and identify business opportunities. • Negotiating patent licenses and settlement agreements. • Representing underwriters in connection with public offerings of over $70 million. PROSECUTION
• Drafting, prosecuting patent applications; directing patent procurement strategy, portfolio management. REPRESENTATIVE LITIGATIONS • Hoffmann-La Roche Inc. and Genentech, Inc. v. Apotex Inc. et al., (N.J.) - Boniva® • Warner Chilcott Co., LLC and Hoffmann-La Roche Inc. v. Teva Pharms. USA, Inc. et al., (Del.) - Actonel® • Unigene Labs., Inc. and Upsher-Smith Labs., Inc. v. Apotex et al., (S.D.N.Y.) - Fortical® • Samuels v. Boston Scientific, (E.D. Tex.) (settled before trial) – endovascular graft REPRESENTATIVE PATENT PROSECUTION, OPINIONS, AND LICENSING SUBJECTS
Pharmaceuticals • medical devices • diagnostics and assays • proteins, polymers, enzymes
cancer therapies • biofuels • food sciences and consumer products • screens and fabrics
WORK EXPERIENCE
Law Clerk NYC DOE • Technical Advisor Lucent Technologies • Researcher Brown University TEACHING EXPERIENCE
Invited Lecturer, Patent Law NYU • Legal Writing (T.A.) Cardozo • Organic Chem (T.A.) Brown Univ. PROFESSIONAL MEMBERSHIPS
New York Intellectual Property Law Association • New York State Bar Association
BAR ADMISSIONS
New York (Oct. 2005) • New Jersey (Dec. 2004) • U.S.P.T.O. (July 2003: Reg. No. 54,649)
COURT ADMISSIONS
C.A.F.C. (Nov. 2010) • S.D.N.Y. (Aug. 2007) • E.D.N.Y. (Aug. 2007) • D.N.J. (Dec. 2004)
EDUCATION Cardozo School of Law J.D. (2004) • Brown University B.S. (honors)Biophysics (2001)
Fun Fact: Joshua Harris is a Beatles / classic rock / progressive rock connoisseur.
Updated Palestinian EDL (Core List) and CDL Vial: 0.25% Injection for spinal anesthesia: 0.5% in 4‐ml amp to be mixed with 7.5% glucose solution Lidocaine HCl + Epinephrine (adrenaline) 1.3 Preoperative medication and sedation for short-term procedures 2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTI-INFLAMMATORY MEDICINES (NSAIMs), MEDICINES USED TO TREAT GOUT AND DISEASE MODIFYING AGENTS I
Skin Care Profile Name ___________________________ Address_______________________________________ City_____________________________ State ______ Zip _________ Date of Birth___________ Email:___________________________ Phone(Day)______________(Night)________________ Profession_____________________ How did you hear about us? _________________________ Your Health 1. Within the last ye