CASE #1070: Application of the FirstLine Therapy™ Therapeutic Lifestyle Changes Program on a Patient with Altered Body Composition 1, 4, and 6 Weeks after Starting the FirstLine Therapy Program
The purpose of this case study was to show how a
therapeutic lifestyle changes program known as First
In the first week, the patient lost 4.5 lb, and was Line Therapy—which includes a dietary program, regular
advised to alternate her breakfast with other meal
exercise, and targeted nutritional support—can be
options, or mix 1 scoop UltraGlycemX with 1 scoop
beneficial in a patient with altered body composition and
After 4 weeks, the patient reported doing well and had
been following the program without any problems.
During the previous 4 weeks, she had switched from
PATIENT'S PRESENTATION AND HISTORY
UltraGlycemX to UltraMeal beverage mix. Her weight
had decreased to 186.5 lb, her body fat had decreased
A 25-year-old Caucasian female presented with concerns
to 39.6%, and her lean mass increased to 60.4%. Her
about her weight. Additionally, she was looking for a
BP was 145/110. Two weeks later, she had lost an
natural therapeutic approach to address her PCOS. Two
years earlier, she had presented to her primary care
physician with complaints of irregular menstrual periods
2.9% Decrease
and hirsutism, and was diagnosed with PCOS. Based on
in Body Fat in 4 Weeks
laboratory results, she was diagnosed with borderline
insulin resistance. She was placed on desogestrel/ethinyl
estradiol tablets (OCP), to be taken cyclically. She was
taking no other prescriptive medications or supplements.
The patient’s past medical history, as well as her family
HT: 62”; WT: 198 lb; BMI†: 36.2 kg/m2; body fat:
Physical exam was unremarkable, except for mild
Figure 1. After 4 weeks, the patient's body fat decreased
from 42.5% to 39.6%. This result suggests a notable
ASSESSMENT AND PLAN
improvement in the patient's body fat mass with the
Assessment: Altered body composition, PCOS, and
2.9% Increase in Lean Body Mass in 4 Weeks
The patient was placed on the First Line Therapy
program, along with supplements to support underlying
issues associated with PCOS, and instructed to begin:
UltraGlycemX Medical Food beverage mix to
nutritionally support healthy blood sugar levels,
Conjugated linoleic acid (CLA) in triglyceride
form to promote healthy body composition,
EPA-DHA 300:200 to support overall health, 1
Figure 2. The patient's lean body mass increased from
UltraMeal Bar Medical Food to promote healthy
57.5% to 60.4% after 4 weeks. This result suggests a
body composition, 1/day (in the afternoon)
noteworthy improvement in the patient's body
A 1300 Cal/day, low-glycemic-index diet,
composition with the FirstLine Therapy program.
8, 10, and 15 Weeks after Starting the FirstLine Therapy Program
The patient continued a steady weight loss at the 8, 10,
The information provided in this case study describes the results
and 13 week visits. After 13 weeks she weighed 172 lb,
of one patient under the care of a licensed healthcare
and her BMI had decreased to 31.5 kg/m2. She reported
practitioner and may not be a typical response. Patients treated with medications should be carefully monitored by their
no new hair growth on her chest, and was anxious to
healthcare practitioner during any changes to their medication
discontinue her OCP. She was advised to discontinue the
Financial support for this study was provided by Metagenics, Inc.
After 15 weeks, the patient's BMI was reduced to 30.5
This study was provided by M onique Class, MS, APRN, BC, and
kg/m2 and she had lost an additional 5 lb, for a total
conducted at the Center for Women's Health, Darien, CT.
weight loss of 31 lb. Her fasting insulin was normal at
FirstLine Therapy is a trademark of Metagenics, Inc.
11.9 µIU/mL (reference range: 6 - 27 µIU/mL), and
fasting glucose was also normal at 80 mg/dL (reference
†Body Mass Index (BMI) is computed by the weight (kg) divided
range: 65-109 mg/dL). The patient's BP had normalized
to 122/80. She was scheduled for a follow-up visit to
assess whether she resumed normal cycling after
2004 Functional Medicine Research Center
Case #1070: Application of the First Line Therapy™ Therapuetic Lifestyle Changes Program on a Patient with Altered Body Composition and Polycystic Ovarian Syndrome (PCOS). Metagenics, Inc; FLT3-1104.
19% Decrease in Body Mass Index in 15 Weeks Figure 3. After 15 weeks, the patient’s body mass index
(BMI) decreased from 36.2 to 30.5 kg/m2. This result
indicates the patient’s BMI considerably improved with
This case study demonstrated dramatic improvements of
BMI, body weight, and insulin control in a female with
altered body composition and PCOS with the application
of the FirstLine Therapy program.
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CASE #1070: Application of the FirstLine Therapy™ Therapeutic