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1. .Product and Company IdentificationMaterial name IBUPROPHEN with N.F. EXCIPIENTS * IBUPROFEN DIRECT COMPRESSION * ALPHA-P-ISOBUTYLPHENYLPROPIONIC ACID with N.F. EXCIPIENTS 2. .Hazards IdentificationEmergency overview Harmful by inhalation and if swallowed. Exposure to powder or dusts may be irritating to eyes, nose and throat. May cause sensitization by skin contact. Dust may form explosive mixture with This product is considered hazardous under 29 CFR 1910.1200 (Hazard Communication).
Inhalation. Ingestion. Skin contact. Eye contact.
Dust or powder may irritate eye tissue. Avoid contact with eyes.
May cause skin irritation. May cause sensitization by skin contact. Avoid contact with the skin.
Harmful by inhalation. Dust irritates the respiratory system, and may cause coughing and difficulties in breathing. Sore throat.
Harmful if swallowed. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. May cause ulceration to the gastrointestinal tract. Dizziness. Rash. Fluid retention.
May cause allergic skin disorders in sensitive individuals.
Ecological injuries are not known or expected under normal use.
3. .Composition / /Information on IngredientsComponents 4. .First Aid MeasuresFirst aid procedures Immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention Wash off with soap and plenty of water. For minor skin contact, avoid spreading material on unaffected skin. Get medical attention if irritation develops and persists.
Material name: DCI®-90 (Ibuprofen USP 90%) MSDS ID: DCI90 Version #: 02 Revision date: 07-13-2012 If gas/fume/vapor/dust/mist from the material is inhaled, remove the affected person immediately to fresh air. Get medical attention if symptoms occur.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Do not induce vomiting without advice from poison control center. Never give anything by mouth to a victim who is unconscious or is having convulsions. Rinse mouth thoroughly. If vomiting occurs, keep head low so that stomach content doesn't get into the lungs.
Oxygen, if needed. Keep victim warm. Symptoms may be delayed.
In the case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Ensure that medical personnel are aware of the material(s) involved, and take 5. .Fire Fighting MeasuresFlammable properties Not flammable by OSHA criteria. Dust may form explosive mixture with air.
Water. Foam. Dry chemical powder. Carbon dioxide (CO2).
Dust may form explosive mixture with air. Fire may produce irritating, corrosive and/or toxic In the event of fire, cool tanks with water spray. Move containers from fire area if you can do so without risk. As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
Cool containers exposed to flames with water until well after the fire is out.
6. .Accidental Release MeasuresPersonal precautions Ventilate the area. Keep unnecessary personnel away. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Wear appropriate protective equipment and clothing during clean-up. Avoid inhalation of dust from the spilled material.
Ventilate closed spaces before entering them.
Prevent further leakage or spillage if safe to do so. Do not contaminate water.
ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Collect spillage. If sweeping of a contaminated area is necessary use a dust suppressant agent which does not react with the product. Prevent entry into waterways, sewer, basements or confined Should not be released into the environment. Sweep up or vacuum up spillage and collect in suitable container for disposal. Avoid dust formation. Collect dust using a vacuum cleaner equipped with HEPA filter. Following product recovery, flush area with water.
DO NOT handle, store or open near an open flame, sources of heat or sources of ignition. Protect material from direct sunlight. Handle under inert gas atmosphere. Minimize dust generation and accumulation. Keep formation of airborne dusts to a minimum. Dust may form explosive mixture with air. Provide appropriate exhaust ventilation at places where dust is formed. Use explosion-proof ventilation equipment. In case of insufficient ventilation, wear suitable respiratory equipment. Take precautionary measures against static discharges. Static electricity and formation of sparks must be prevented. All equipment used when handling the product must be grounded. Ground and bond containers when transferring material. Use non-sparking tools and explosion-proof equipment. Do not breathe dust. Avoid contact with eyes. Avoid prolonged exposure. Wash hands thoroughly after handling. Avoid release to the environment.
Store in a well-ventilated place. Keep container tightly closed. Keep away from moisture. Keep from freezing. Guard against dust accumulation of this material. This material can accumulate static charge which may cause spark and become an ignition source. Prevent electrostatic charge build-up by using common bonding and grounding techniques. Keep away from heat, sparks and open flame. Use care in handling/storage.
Material name: DCI®-90 (Ibuprofen USP 90%) MSDS ID: DCI90 Version #: 02 Revision date: 07-13-2012 8. .Exposure Controls / /Personal ProtectionOccupational exposure limits Explosion-proof general and local exhaust ventilation. Good general ventilation (typically 10 air changes per hour) should be used. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits. If exposure limits have not been established, maintain airborne levels to an acceptable level. If engineering measures are not sufficient to maintain concentrations of dust particulates below the OEL, suitable respiratory protection must be worn. If material is ground, cut, or used in any operation which may generate dusts, use appropriate local exhaust ventilation to keep exposures below the recommended exposure limits. Ensure adequate ventilation, especially in confined areas.
Chemical goggles are recommended. Provide eyewash station and safety shower. Avoid contact Avoid contact with the skin. Wear suitable protective clothing. Chemical resistant gloves.
If airborne concentrations are above the applicable exposure limits, use NIOSH approved respiratory protection. Wear respirator with dust filter.
When using, do not eat, drink or smoke. Do not breathe dust. Avoid contact with eyes. Avoid contact with skin. Handle in accordance with good industrial hygiene and safety practice.
9. .Physical & Chemical PropertiesAppearance Material name: DCI®-90 (Ibuprofen USP 90%) MSDS ID: DCI90 Version #: 02 Revision date: 07-13-2012 % by volumeFlammability limits in air, lower, When heated to decomp, emits acrid smoke and fumes.
1 . .Chemical Stability & Reactivity InformationChemical stability Material is stable under normal conditions.
1 . .Toxicological InformationToxicological dataComponents Acute Oral LD50 Mouse: 740 mg/kgAcute Oral LD50 Rat: 636 mg/kg May cause sensitization by skin contact.
Harmful if inhaled. Harmful if swallowed.
Inhalation of dusts may cause respiratory irritation.
This product is not considered to be a carcinogen by IARC, ACGIH, NTP, or OSHA.
A4 Not classifiable as a human carcinogen.
This product has no known eco-toxicological effects.
An environmental hazard cannot be excluded in the event of unprofessional handling or disposal.
No data is available on the degradability of this product.
1 . .Disposal ConsiderationsDisposal instructions This product, in its present state, when discarded or disposed of, is not a hazardous waste according to Federal regulations (40 CFR 261.4 (b)(4)). Under RCRA, it is the responsibility of the user of the product to determine, at the time of disposal, whether the product meets RCRA criteria for hazardous waste. Dispose in accordance with all applicable regulations.
Material name: DCI®-90 (Ibuprofen USP 90%) MSDS ID: DCI90 Version #: 02 Revision date: 07-13-2012 1 . .Transport InformationDOTNot regulated as dangerous goods.
IATANot regulated as dangerous goods.
IMDGNot regulated as dangerous goods.
1 . .Regulatory InformationUS federal regulations This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication All components are on the U.S. EPA TSCA Inventory List.
CERCLA/SARA Hazardous Substances - Not applicable.
Drug Enforcement Administration (DEA). List 2, Essential Chemicals (21 CFR 1310.02(b) and 1310.04(f)(2) Drug Enforcement Administration (DEA). List 2, Essential Chemicals (21 CFR 1310.02(b) and 1310.04(f) Drug Enforcement Administration (DEA). List 1 & 2 Exempt Chemical Mixtures (21 CFR 1310.12(c)) Superfund Amendments and Reauthorization Act of 1986 (SARA) Australian Inventory of Chemical Substances (AICS) Inventory of Existing Chemical Substances in China (IECSC) European Inventory of Existing Commercial Chemical European List of Notified Chemical Substances (ELINCS) Inventory of Existing and New Chemical Substances (ENCS) Philippine Inventory of Chemicals and Chemical Substances Toxic Substances Control Act (TSCA) Inventory *A "Yes" indicates that all components of this product comply with the inventory requirements administered by the governing country(s) Material name: DCI®-90 (Ibuprofen USP 90%) MSDS ID: DCI90 Version #: 02 Revision date: 07-13-2012 This product does not contain a chemical known to the State of California to cause cancer, birth US - Pennsylvania RTK - Hazardous Substances: Listed substance WARNING! Harmful if inhaled or swallowed. Exposure to powder or dusts may be irritating to eyes, nose and throat. May cause sensitization by skin contact. Dust may form explosive mixture Avoid breathing dust. Keep container closed. Use only with adequate ventilation. Avoid dust close to ignition sources. Wash thoroughly after handling.
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. If gas/fume/vapor/dust/mist from the material is inhaled, remove the affected person immediately to fresh air. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
Mallinckrodt provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
This document has undergone significant changes and should be reviewed in its entirety.
Material name: DCI®-90 (Ibuprofen USP 90%) MSDS ID: DCI90 Version #: 02 Revision date: 07-13-2012

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