Tadalafil entfaltet seine Wirkung über eine selektive Hemmung der PDE5, wodurch die Konzentration von cGMP im glatten Muskelgewebe stabil bleibt. Diese biochemische Modulation resultiert in einer langanhaltenden Relaxation der Gefäßwände. Der Wirkstoff wird nach oraler Einnahme effizient resorbiert, mit einer Bioverfügbarkeit von rund 80 %. Seine Halbwertszeit von bis zu 36 Stunden ist innerhalb dieser Substanzklasse außergewöhnlich. Abgebaut wird er in der Leber, hauptsächlich durch CYP3A4, mit anschließender biliärer Exkretion. Typische unerwünschte Wirkungen entstehen durch eine verstärkte Vasodilatation, etwa Kopfschmerzen oder Flush. Pharmakologisch wird cialis generika vor allem durch die verlängerte Wirkungsdauer charakterisiert.

Prograf w8400

PROGRAF W8400
Specification
Printer Type:
Bubble Jet on Demand/FINE, End User Replaceable (BC-1350), 6-Color Print Head* Print Speed (up to):
Wide Size: Plain Paper (Standard Mode), 117 Square Feet Per Hour** Wide Size: Heavyweight Coated Paper (Standard Mode), 118 Square Feet Per Hour** Wide Size: Glossy Photo Paper (Standard Mode), 91 Square Feet Per Hour** Number of Nozzles:
Nozzle Text: 1,280 Nozzles per Colour; 7,680 Nozzles Total Nozzle Pitch:
Nozzle Recovery System:
Non-firing Nozzle Detection and Compensation Print Resolution (up to):
OS Compatibility:
Windows® 98/ME/NT® 4.0 SP6/2000/XP/2003 Server and Mac OS (8.6 to 9.x), Mac OS X version 10.2.5 to 10.3.x. Standard Interface:
USB 2.0 Hi-Speed, 10/100 Base -T/TX. Optional: IEEE1394 Firewire Card* Ink Compatibility:
Cyan, Magenta, Yellow, Black*, Matte Black*, Photo Cyan, Photo Magenta Ink Droplet Size:
Ink Capacity:
Ink Types:
Maximum Paper Size:
Maximum Roll Print Length: 59 Feet (18 meters); Maximum Media Roll Diameter: 5.9" (150mm) Media Width:
Media Thickness:
Margins:
Margin: Roll: All sides, 5mm (0.20") Maximum Roll Print Length: 59 Feet (18 meters)
Maximum Media Roll
Diameter:
Borderless Printing Width
10", 14", 16", 24", 36", 42" 594mm (ISO A1), 840mm(ISO A0), 515mm(JIS B2), (Roll Media Only):
Languages:
Language: Printer: GARO (Canon Proprietary) via Software RIP: PostScript, PDF 1.4, EPS, TIFF, JPEG, BMP Physical Dimensions:
(With Stand) 64.6" W x 38.2" D x 42.3" H Power Source:
Operating Environment:
Humidity: RH 10 - 80 % (No condensation) User-replaceable items:
Item: Print Head, Maintenance Cartridge, Cutter Blade Warranty:
The imagePROGRAF W8400 Printer Limited Warranty is effective for a period of one year following delivery to the original purchaser. No warranty is given for any consumables, such as paper, ink cartridges and print heads. Software Included:
Printer Driver 2005, Print Plug-in for Photoshop® , HDI Driver for AutoCAD®. PosterArtist†, Digital Photo Print Pro‡ PhotoPRINT Select® for imagePROGRAF (Adobe® PostScript® 3™) * Select regular black or matte black. Interchangeable. ** Square Feet Per Hour does not include data transfer time and time for media cutting. The test conducted here is a result of Canon Inc. internal testing. The actual print speed varies depending on number of factors such as data size, data complexity, application software, and interface. *** For imagePROGRAF Printer Driver 2005. For printing from PostScript® application such as Adobe® Illustrator® or QuarkXPress®, use PhotoPRINT® Select for imagePROGRAF software RIP. **** Available 3Q, 2005 † Windows® 98/Me/2000/Xp only ‡ Windows® 2000/Xp only

Source: http://www.rbdigital.ca/images/pdf/canon%20W8400.pdf