Abel Murillo M.D.
Advanced Intervention & Pain Management Research Clinic
EDUCATION:
Department of Anesthesiology, Perioperative Medicine and Pain Management
University of Miami/Jackson Memorial Hospital
Department of Anesthesiology, Perioperative Medicine and Pain Management
University of Miami/Jackson Memorial Hospital
POST-GRADUATE TRAINING:
1999 to
University of Miami/Jackson Memorial Hospital
University of Miami/Jackson Memorial Hospital
University of Miami/Jackson Memorial Hospital
Abel Murillo, M.D. Curriculum Vitae Page 2 WORK EXPERIENCE: 2005
Advanced Intervention & Pain Management Research Clinic
University of Miami/Jackson Memorial Hospital
Anesthesiology and Pain Medicine Department
University of Miami/Jackson Memorial Hospital
University of Miami/Jackson Memorial Hospital
University of Miami/Jackson Memorial Hospital
University of Miami/Jackson Memorial Hospital
Liver, Kidney, Kidney-Pancreas and Small Bowel Transplant Service
Research Associate and Clinical Coordinator
Abel Murillo, M.D. Curriculum Vitae Page 3 WORK EXPERIENCE continued:
1988 to LICENSES/CERTIFICATIONS: State of Florida Board of Medicine, # ME 86760 Diplomat, American Academy of Pain Management ECFMG # 0-454-373-2 Physician-Surgeon: Professional Title from the Greater National University of San Marcos. Lima, Peru. PROFESSIONAL MEMBERSHIP/ORGANIZATIONS:
American Academy of Pain Management American Society of Anesthesiologists International Anesthesia Research Society Florida Society of Anesthesiology Society of Cardiovascular Anesthesiologists Society for Pediatric Anesthesia Society for Ambulatory Anesthesia American Society of Regional Anesthesia Scottish rite of Freemasonry Southern Jurisdiction. USA PUBLISHED ARTICLE: Azithromycin and Terfenadine: Lack of drug interaction, a double-blind, placebo-controlled study. J. Alderman; D.J. Greenblatt; J. Allison (South Florida Bioavailability Clinic, Miami, Florida); S. Preskorn; W. Harrison; M. Chung. Ipramine Pharmacokinetics with the Selective Serotonin reuptake Inhibitors (SSRIs), Paroxetine or Sertraline. Siepman, N; Blahunka, KS; Harris, SI (South Florida Bioavailability Clinic, Miami, Florida); Palmer, RN. ECG Changes observed following multiple dose Co-administration of Clarithromycin and Terfenadine.
Abel Murillo, M.D. Curriculum Vitae Page 4 PUBLISHED ARTICLE continued: Preskorn S., M.D., Alderma J., PhD., Chung M. , PhD., Harrison W., M.D., Messig M., PhD and Harris S., M.D. (South Florida Bioavailability Clinic, Miami, Florida. Pharmacokinetics of Desipramine Coadministered with Sertraline or Fluoxetine. Journal of Clinical Psycopharmacology. Vol 14 No. 2. 1993. RESEARCH EXPERIENCE:
Multiple dose bioavailability of a sustained release 180 mg xxxx formulation dosed once daily compared to 90 mg xxxx dose every twelve hours in normal healthy volunteers.
Evaluation of three sustained release 180 mg formulations of xxxx in normal healthy volunteers.
A single dose study in healthy volunteers to determine whether 10 mg and 20 mg market image tacrine HCL (CI-970) capsules are bio-equivalent to 20 mg tacrine HCL capsules used in clinical trails.
A definitive study evaluating the relative bioavailability of Terfenadine, Pseudoephedrine and Acetaminophen in fasting and non-fasting subjects receiving single doses of seldane “LOTAP:
An open label study to evaluate the relative bioavailability of Acetaminophen from a test granulette formulation compared with children’s Tylenol elixir in healthy normal male volunteers.
An evaluation of the relative bioavailability of a test formulation of xxxx capsule USP (400 mg) compared with xxxx DS (400 mg) in healthy male volunteers.
Single dose Bioequivalence study of xxxx/xxxx 25/250 mg tablets.
Multiple dose bioavailability of 90 mg Cardizem SR dosed every twelve hours compared to a sustained release 180 mg Diltiazem formulation dosed once daily in normal healthy volunteers (pilot study).
Single dose bioavailability of Diltiazem from three sustained released 180 mg formulation in normal healthy volunteers
A pilot study evaluating the relative bioavailability of single doses of three batches of Seldane “LOTAP” tablets against the individual ingredients administered concomitantly.
A pilot study evaluating the comparative bioavailability of three batches of Terfenadine 60 mg tablets.
A definitive study evaluating the comparative bioavailability of a peppermint flavored (60 mg dose) Terfenadine/Oleic Acid Micellular Liquid formulation (3 mg/ml) and a (60 mg dose) Terfenadine tablet when administered BID for 7.5 days
A definitive study evaluating the relative bioavailability of Terfenadine, Pseudoephedrine HCL, and regular strength Acetaminophen when administered concomitantly and in a combination tablet QID for 7.5 days.
Abel Murillo, M.D. Curriculum Vitae Page 5 RESEARCH EXPERIENCE continued:
Single dose amiloride HCL/Hydrochlorothiazide (5/50) tablets bio-equivalence study administered to healthy male volunteers.
A comparison of the bioavailability of ICU manufactured Atenolol/Hydrochlorothiazide/Triamterene (25mg / 25m / 50mg and 50mg / 25mg / 50mg) fixed combination tablets and the co-administration of Tenormin (50 mg) tablets with a fixed combination Hydrochlorothiazide (25 mg) + Trimterene (50 mg) capsule.
A clinical bio-equivalence study of 100 mg Minocycline HC1 tablets.
A pilot study evaluating the relative bioavailability of single doses of Terfenadine, pseudoephedrine HC1, and Ibuprofen administered concomitantly and in waxed and unwaxed combination tablets.
A definitive study evaluating the relative bioavailability of single doses of Terfenadine 2 x 30 mg tablets and Terfenadine 1 x 60 mg tablets.
A clinical bioequivalence study of Acetaminophen.
A pilot bioequivalence evaluation of a conjugated estrogen product compared with premarin in six post-menopausal female volunteers.
A pilot study to determine the bioequivalence of a single dose of Erythomycin mg.250 capsules and ERYC mg.250 in healthy volunteers.
A definitive study evaluating the relative bioavailability of Terfenadine, Psedoephedrine HC1, and extra-strength acetaminophen when administered concomitantly and in a combination tablet QID for 7.5 days.
The multiple dose pharmacokinetics and pharmacodynamics of Glipizide after administration of Glipizide gits (20 mg QD) to elderly patients with non-insulin dependent diabetes mellitus.
Doxazosin tablet study, Doxazosin pharmacokinetics: Morning versus evening study.
Multiple sustained release verapamil products.
Single rising dose Pharmacokinetic/Toleration study of Tandospirone gits formulation in healthy male volunteers.
Bio-equivalence study of three lots of Prazosin XL tablets.
A placebo-controlled, double-blind, parallel group Cardiac safety and Pharmacokinetic study of multiple doses of xxxx in healthy male volunteers.
A study evaluating the interaction potential of Clarithromycin and Terfenadine following multiple dosing.
Abel Murillo, M.D. Curriculum Vitae Page 6 RESEARCH EXPERIENCE continued:
Bio-equivalence study of three different production lots of Procardia XL tablets.
Ascending Single-Dose Safety, Tolerance, and Preliminary Pharmacokinetic study of xxxx capsules in Normal Male Subjects.
Oral Safety and Toleration and the Dose Proportionality of Acetyl-L-Carnitine Hydrochloride at Steady-State in Male and Female Patients Diagnosed with Non-Insulin Dependent Diabetes Mellitus.
Oral Safety and Toleration and the Dose Proportionality of Acetyl-L-Carnitine Hydrochloride at Steady-State in Male and Female Patients Diagnosed with Insulin Dependent Diabetes Mellitus.
Bioavailability of Dolasetron after Co-Administration with Cimetidine and Rifampin in Normals.
A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose, Safety, Tolerance, and Pharmacokinetic study of CL 329,167, Administered as an Oral Solution, in Adult Mild-to-Moderate Hypertensive Patient for Two Weeks.
Study of the effects of food on the Pharmacokinetics of Pre-Marin Tablets and MPA Tablets administered concomitantly in healthy Post-menopausal female subjects.
Pharmacokinetics of Ciporfloxacin and Metronidazole given concurrently in healthy subjects.
Determining the concentration of Acetyl-L-Carnitine and Free Carnitine in sural nerve tissue in relaton to plasma concentrations Acetyl-L-Carnitine and free Carnitine after dosing to Steady-State with Acetyl-L-CarnitineHydrochloride in Male and Female Patients Diagnosed with either Non-Insulin Dependent or Insulin Dependent Diabetes Mellitus.
A multiple dose bio-equivalency study of the 20 mg Glipizide GITS commercial tablets vs. the 20 mg Glipizide GITS Research tablets in subjects with Non-Insulin Dependent Mellitus.
A comparative bioavailability study of a Pre-marin Tablet and a Medroxy-proesterone Acetate Encapsulated Tablet Administered Concomitantly vs. a Single combination tablet formulation.
A double blinded, placebo controlled, two way crossover study to evaluate the action of xxxx in Glyburide treated adult volunteers with non-insulin dependent diabetes mellitus.
A Pharmacokinetic study for Clotrimazole Vaginal Tablets following multiple doses in patients with symptoms of Vaginal Candidiasis.
Multiple dose interaction study of Desipramine (50 mg QD) with Sertraline (50 mg QD) or Paroxetine (20 mg QD) in healthy adult volunteers.
A Randomized, Placebo Controlled, Double Blind, study of Lozol (Indapamide) 1.25 mg once daily in elderly patient with mild to moderate hypertension.
Abel Murillo, M.D. Curriculum Vitae Page 7 RESEARCH EXPERIENCE continued:
A Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group assessment of the dose response and safety of xxxx administered once daily for 28 days.
A comparative multiple dose Pharmacokintic/Pharmacodynamic study of Procardia XL (Pfizer) and Adalt cc (miles) in Mild and Moderate Hypertensive subjects
A Double-Blinded, Placebo-Randomized, 4-period crossover dose escalating Pharmacodynamic and safety study of xxxx in Normal Subjects.
Determination of Bio-equivalence under fasted conditions of xxxx tablets manufactured by Searle at two sites.
A comparative Bio-equivalence study of Hydrodiuril (hydrochlorothiazide) 2 x 25 mg tablets in healthy men.
Bio-equivalence study of 4 mg doxazosin tablets and capsules.
The effect of Grapefruit juice on the Pharmacokinetics of Amlodipine in normal volunteers.
Double-blind Randomized dose acceleration efficacy and tolerance study of Doxazosin vs. Placebo in patients with Milt to Moderate Primary Hypertension.
A Double-blind, multiple dose, randomized, placebo-controlled, parallel group hemdynamic drug interaction study between xxxx and Nifedipine in male patients with essential hypertension.
Pharmacokinetics of Sertraline and Fluoxetine when Fluoxetine administration is switched to Sertraline in depressed patients.
A Pharmacokinetic study evaluating the interaction potential of Terfenadine and Fluconazole.
A placebo-controlled, double-blind, parallel group cardiac safety and pharmacokinetic study of multiple doses of Ebastine in healthy male volunteers.
Bio-equivalence study of Prazosin GITS tablets coated at three different production facilities.
Pilot multiple dose pharmacokinetic/toleration study of Tandospirone Gits formulation in healthy male volunteers.
A pharmacokinetic study evaluating the interaction potential of Terfenadine 2 x 60 mg QD and Erythromycin 500 mg QID following multiple dosing.
An open-label interaction study between a single dose of Ebastine and a multiple dose of Ketoconazole on the cardiac function and pharmacokinetic profile in healthy adult male volunteers.
An open-label, replicate design, randomized, four-way crossover pharmacokinetic and pharmacodynamic comparison of single and multiple dose (I.E. Steady-Sate) Calan SR versus generic extended release Verapamil HCL under Fed conditions in young, healthy male subjects.
Abel Murillo, M.D. Curriculum Vitae Page 8 RESEARCH EXPERIENCE continued:
Comparison of the bioavailability of three xxxx controlled release tablet formulations with an immediate release tablet formulation.
A comparative Bio-equivalence study of Hydrodiuril (Hydrochlorothiazide) 2 x 25 mg tablets ground and encapsuled vs Hydrodiuril 2 x 25 mg tablets in healthy men.
Study to determine the Bio-equivalence of a sugar coated tablet formulation containing 50 mcg Levonorgestrel and 30 mcg Ethinyl Estradiol relative to the Wyeth-Ayerst manufactured sugar coated Tri-Levien tablets containing the same amounts of Levonorgestrel and Ethinyl Estradiol.
A Placebo-Controlled trail assess the safety, tolerance and pharmacokinetics of ascending oral doses of Zenca ZD7288 in subjects with coronary artery disease.
A Study of the effects of food on the pharmacokinetics of pre-marin (0.625 mg) /MPA (2.5 mg) combination tablets in healthy post-menopausal female subjects.
A single center, randomized, open parallel, placebo-controlled efficacy study of trough serum potassium levels with 40 meq K-Dur in single or divided doses in Hypertensive patients with a predisposition to diuretic induced Hypokalemia.
__________________________
FDA Conducts Preliminary Review of Agency’s Diversion and Counterfeit Criminal Case Information September 2011 “Drug counterfeiting, diversion, cargo theft and economically motivated adulteration are crimes of opportunity, and the opportunity is flourishing because of the dramatic way our world has changed in a relatively short period of time.” Executive Summary T
QUESTIONNAIRE DÉMOGRAPHIQUE Date/Expérimentateur__________________________________________ Screening: Informations démographiques générales RAPPELER AU PARTICIPANT LE POTENTIEL DE CONFIDENTIALITÉ Code assigné au participant, si éligible ________________ Avez-vous déjà participé à une étude au Centre d’étude sur le stress humain? Si oui, pouvez-vous vous rap